Twisting BMI1
نویسندگان
چکیده
منابع مشابه
BMI1, ATM and DDR
The polycomb group protein BMI1 is a component of the polycomb repressive complex 1 (PRC1). Although lacking enzymatic activity, BMI1 makes an important contribution to the intrinsic E3 ubiquitin ligase activity of PRC1 via binding of the catalytic subunit RING2. PRC1 catalyzes mono-ubiquitination of histone H2A at lysine 119 (H2AK119Ub), a well-recognized epigenetic marker associated with gene...
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We introduce the concept of pseudotwistor (with particular cases called twistor and braided twistor) for an algebra (A,μ, u) in a monoidal category, as a morphism T : A⊗ A → A ⊗ A satisfying a list of axioms ensuring that (A,μ ◦ T, u) is also an algebra in the category. This concept provides a unifying framework for various deformed (or twisted) algebras from the literature, such as twisted ten...
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The scenery of the nucleus The nucleoplasm is no less dense, even though it contains neither membrane nor rigid filament. However, it contains one remarkable type of filament, the DNA, which, for a mammalian cell with a small nucleus, can account for close to 10% (100 mg m1-1) of the nuclear mass (including water). This is a very high concentration much higher than that generally used for exper...
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This article is devoted to the investigation of the deformation (twisting) of monoidal structures, such as the associativity constraint of the monoidal category and the monoidal structure of monoidal functor. The sets of twistings have a (non-abelian) c ohomological nature. Using this fact the maps from the sets of twistings to some cohomology groups (Hochschild cohomology of K-theory) are cons...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2010
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc2940